Shizue   Mito

Assistant Professor  

Office: ESCNE 3.112
Phone: (956) 665-8740
Email: shizue.mito@utrgv.edu
Website: faculty.utrgv.edu/shizue.mito/lab/home.html

Shizue Mito





Selected Publications


  • Benxu Cheng, Lisa Morales, Yonghong Zhang, Shizue Mito, and Andrew Tsin. "Niclosamide induces protein ubiquitination and inhibits multiple pro-survival signaling pathways in the human glioblastoma U-87 MG cell line ," PLoS ONE 12, no. 9 (September 2017): e0184324.

  • Quang Luu, Jorge Guerra, Cecilio Castaneda, Manuel Martinez, Jong Saunders, Benjamin Garcia, Brenda Gonzales, Anushritha Aidunuthula, and Shizue Mito. "Ultrasound assisted one-pot synthesis of benzo-fused indole-4, 9-dinones from 1, 4-naphthoquinone and $α$-aminoacetals," Tetrahedron Letters 57, no. 21 (2016): 2253–2256.

  • Quang Luu and Shizue Mito. "Preparation of indolequinones and their applications in organic synthesis," Tetrahedron 71, no. 6 (2015): 895–916.

  • Diego Pedroza, Fernando De Leon, Armando Varela, Fresia Lema, Renato Aguilera, and Shizue Mito. "The Cytotoxic Effect of 2-Acylated-1,4-Naphthohydroquinones on Leukemia/Lymphoma Cells," Bioorganic & Medicinal Chemistry 22, no. 2 (January (1st Quarter/Winter) 2014): 842-7.

  • Fernando De Leon, Sudhakar Kalagara, Ashley Navarro, and Shizue Mito. "Synthesis of 6-Acyl-5,8-quinolinediols by Photo-Friedel-Crafts Acylation Using Sunlight," Tetrahedron Letters 54, (2013): 3147-3149.

  • David Evans, Shizue Mito, and Daniel Seidel. "Scope and mechanism of enantioselective Michael additions of 1, 3-dicarbonyl compounds to nitroalkenes catalyzed by nickel (II)- diamine complexes," Journal of the American Chemical Society 129, no. 37 (2007): 11583–11592.

  • Shizue Mito, Lishan Zhou, Chanjuan Xi, and Tamotsu Takahashi. "Reaction of Zirconocene–Alkyne Complexes with Mo (CO) 6," Chemistry letters 35, no. 1 (2006): 122–123.

  • Shizue Mito and Tamotsu Takahashi. "Double carbonylation of zirconocene–alkyne complexes," Chemical communications no. 19 (2005): 2495–2496.

  • Zhenfeng Xi, Hong-Tao Fan, Shizue Mito, and Tamotsu Takahashi. "CO insertion reaction of zirconacyclopentadienes," Journal of organometallic chemistry 682, no. 1 (2003): 108–112.

  • Zhenfeng Xi, Ruiyun Guo, Shizue Mito, Hongliang Yan, Ken-ichiro Kanno, Kiyohiko Nakajima, and Tamotsu Takahashi. "One-pot synthetic routes to multiply substituted indene derivatives by hydrolysis of zirconocene-mediated intermolecular coupling reactions of aromatic ketones and alkynes," The Journal of organic chemistry 68, no. 4 (2003): 1252–1257.



Selected Grants and Fellowships


  • Shizue Mito. Enhancement of Advanced Organic Chemistry Course with the UTEP library Database, Other, $3,000.00 (September 1, 2014 - May 31, 2015)

  • Shizue Mito. Photochemical Reactions of 1,4-Quinones with Sunlight, Other, $5,000.00 (September 1, 2012 - August 31, 2013)

  • Shizue Mito. Transition Metal Mediated One-Pot Three-Component Synthesis of gamma-Amino Acids, Other, $160,000.00 (June 1, 2010 - May 31, 2013)

  • Shizue Mito. TRANSITION METAL MEDIATED ONE-POT THREE-COMPONENT SYNTHESIS OF Y-AMINO ACIDS, WELCH FOUNDATION, $160,000.00 (June 1, 2010 - May 31, 2012)

  • Shizue Mito. Development of New Synthetic Method for Amino Acid Derivatives with Carbon Dioxide , Other, $4,987.00 (January 1, 2009 - December 31, 2009)



Selected Presentations


  • Shizue Mito. "Synthesis of p-indolequinones and their bioactivities," 2018 COS Research Conference, College of Science, University of Texas at San Antonio, San Antonio, TX (October 2018)

  • Shizue Mito. "Fomal synthesis of Syringolide1," ACS National Meeting, American Chemical Society, Boston MA (August 2018)

  • Shizue Mito. "Synthesis of Bioactive Quinone Derivatives," Departmental Seminar, Tokushima University, Tokushima, Japan (January 2018)

  • Shizue Mito, Benjamin Garcia, Liza Morales, and Yonghong Zhang. "SYNTHESIS AND STRUCTURE–ACTIVITIY RELATIONSHIP STUDY OF NICLOSAMIDE DERIVATIVES IN PROTEIN UBIQUIRINATION AND PRO-SURVIVAL SIGNALING PATHWAYS IN THE IN THE HUMAN GLIOBLASTOMA CELLS," The UTRGV SoM Inaugural Research Symposium 2017, School of Medicine, University of Texas Rio Grande Valley, Edinburg (August 2017)

  • Shizue Mito. "One-pot synthesis of benzo-fused p-indolequinones from naphthoquinone," ACS National Meeting, American Chemical Society, Philadelphia, PA (August 2016)

  • Shizue Mito. "One-pot Synthesis of α-Amino Acid Using CO2 via Zirconaaziridine," ACS National Meeting, American Chemical Society, San Francisco, CA (August 2014)

  • Shizue Mito. "Synthesis of hetrocycles by sunlight," ACS Southwest Regional Meeting, American Chemical Society, Waco, TX (November 2013)

  • Sudhakar Kalagara and Shizue Mito. "Total synthesis of Syringolides," 245th ACS National Meeting and, New Orleans, LA. (April 2013)

  • Shizue Mito. Departmental Seminar, Texas Christian University, Fort Worth, TX (April 2013)

  • Shizue Mito. Departmental Seminar, University of Texas at Arlington, Arlington, TX (April 2013)

Current Courses

CHEM 2125 02 - Organic Chemistry II Lab:
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CHEM 7300 06 - Thesis I:
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CHEM 2125 06 - Organic Chemistry II Lab:
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CHEM 2325 03 - Organic Chemistry II:
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CHEM 2125 07 - Organic Chemistry II Lab:
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CHEM 6330 01I - Sp Top in Organic Chemistry:
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CHEM 7300 06 - Thesis I:
Syllabus
Course Evaluations
Textbooks
CHEM 2325 01 - Organic Chemistry II:
Syllabus
Course Evaluations
Textbooks
CHEM 6330 02I - Sp Top in Organic Chemistry:
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CHEM 4378 03I - Special Topics in Chemistry:
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Previous Courses