Andreas   Hanke

Professor  

Office: BLHSB 2.220
Phone: (956) 882-6682
Email: andreas.hanke@utrgv.edu

Dr. Andreas Hanke

I studied physics and mathematics at the Ludwig Maximilian University of Munich, and received my PhD in physics at University of Wuppertal, Germany. After postdocs at MIT (USA), Oxford University (UK), and University of Stuttgart (Germany) I joined the Physics Department of UTB in 2004. I am currently Professor at the Physics Department of UTRGV.





Selected Publications


  • A Hanke, L Shokri, I Rouzina, and M Williams. "Binding of Ethidium Bromide to DNA probed by Single-Molecule Force Spectroscopy," Nucl. Acids Res. (2018).

  • Andreas Hanke, Riccardo Ziraldo, and Stephen Levene. "Kinetic Pathways of Topology Simplification by Type-II Topoisomerases in Knotted Supercoiled DNA," Nucl. Acids Res. (2018).

  • M Shoura, S Giovan, A Vetcher, A Hanke, and S Levene. "Loop-closure Kinetics Reveal a Stable Right-handed DNA Intermediate in Cre Recombination," Nat. Struct. Mol. Biol (2018).

  • Andreas Hanke, Riccardo Ziraldo, and Stephen Levene. "Kinetic Pathways of Topology Simplification by Type-II Topoisomerases in Knotted Supercoiled DNA," Biophys. J., 114, no. Supplement 1 May 2018: 443a.

  • S Giovan, A Hanke, and S Levene. "DNA cyclization and looping in the wormlike limit: normal modes and the validity of the harmonic approximation," Biopolymers 103, (2015): 528.

  • S Giovan, R Scharein, A Hanke, and S Levene. "Free Energy Calculations for Semi-flexible Macromolecules: Applications to DNA Knotting and Looping," J. Chem. Phys. 141, (2014): 174902.

  • A Hanke. "Denaturation transition of stretched DNA," Biochem. Soc. Trans. 41, (2013): 639.

  • A Hanke. "Non-Equilibrium Casimir Force between Vibrating Plates," Plos One 8, (2013): e53228.

  • S Levene, S Giovan, A Hanke, and M Shoura. "The thermodynamics of DNA loop formation, from J to Z," Biochem. Soc. Trans. 41, (2013): 513.

  • A Hanke, S Giovan, and S Levene. "Evaluating Partition Functions for Multiscale Models of DNA," Prog. Theor. Phys. Suppl. 191, (2011): 109.



Selected Grants and Fellowships


  • Andreas Hanke. Single-Molecule DNA Topology, NIH, $286,400.00 (August 1, 2015 - April 30, 2019)

  • Andreas Hanke. Thermodynamics and kinetics of DNA-ligand binding probed by DNA overstretching, NIH, $400,364.00 (August 15, 2013 - July 31, 2018)

  • Andreas Hanke. Acquisition of two GPU workstations to carry out atomistic molecular dynamics simulations of DNA and other biomolecules, Higher Education Assistance Fund (HEAF), $12,800.00 (July 2014)

  • Andreas Hanke. Thermodynamics and kinetics of DNA binding proteins probed by DNA overstretching, NIH, $412,183.00 (May 1, 2008 - May 30, 2012)



Selected Presentations


  • Andreas Hanke. "Dynamical Casimir effect in a periodic lattice of superconducting microwave circuits," Conference: Fascination with fluctuations, correlations, and disorder, MIT, USA (June 2018)

  • Andreas Hanke. "Kinetic Pathways of Topology Simplification by Type-II Topoisomerases in Knotted, Supercoiled DNA," Biophysical Society 62nd Annual Meeting, San Francisco, CA, USA (February 2018)

  • Andreas Hanke. "Kinetic Pathways of topology simplification by type-II topoisomerases in knotted, supercoiled DNA," UTRGV Physics Colloquium, UTRGV (October 2017)

  • Andreas Hanke. "DNA Topology Simplification by DNA topoisomerases: A Survey," Seminar, University of Texas at Dallas, TX, USA, (August 2016)

  • Andreas Hanke. "DNA Topology Simplification by DNA topoisomerases," Seminar, University of Texas at Dallas, TX, USA, (March 2016)

  • Andreas Hanke. "Multiscale Modeling of Macromolecular Systems in Biology," Seminar, University of Texas at Brownsville, TX, USA, (November 2014)

  • Andreas Hanke. "Mysterious forces between ships in wavy waters," Monday Night Physics, University of Texas at Brownsville, TX, USA, (October 2014)

  • Andreas Hanke. "Multiscale Modeling of Macromolecular Systems in Biology," Seminar, University of Texas at Dallas, TX, USA, (January 2014)

  • Andreas Hanke. "Direct Free-Energy Calculations for Semiflexible Macromolecules: Applications to DNA Knotting and Looping," Seminar, Northeastern University, Boston, MA, USA, (September 2013)

  • Andreas Hanke. "Denaturation Transition of stretched DNA in the Presence of DNA-Binding Ligands," Topological Aspects of DNA Function and Protein Folding, Isaac Newton Institute for Mathematical Sciences, Cambridge University, Cambridge, UK, (September 2012)

Current Courses

PHYS 7301 04 - Thesis II:
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PHYS 5310 01 - Classical Mechanics I:
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PHYS 3303 01I - Thermodynamics:
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PHYS 3303 02I - Thermodynamics:
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Previous Courses